Cargando…

Integrin α9 Suppresses Hepatocellular Carcinoma Metastasis by Rho GTPase Signaling

Integrin subunit alpha 9 (ITGA9) mediates cell-cell and cell-matrix adhesion, cell migration, and invasion through binding different kinds of extracellular matrix (ECM) components. However, its potential role and underlying molecular mechanisms remain unclear in hepatocellular carcinoma (HCC). Here,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yan-Li, Xing, Xin, Cai, Li-Bo, Zhu, Lei, Yang, Xiao-Mei, Wang, Ya-Hui, Yang, Qin, Nie, Hui-Zhen, Zhang, Zhi-Gang, Li, Jun, Zhang, Xue-Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989280/ https://www.ncbi.nlm.nih.gov/pubmed/29951557 http://dx.doi.org/10.1155/2018/4602570

Ejemplares similares

DNA methylation-mediated silencing of matricellular protein dermatopontin promotes hepatocellular carcinoma metastasis by α3β1 integrin-Rho GTPase signaling
por: Fu, Ying, et al.
Publicado: (2014)

Rho Gtpases: Integrating Integrin Signaling
por: Ridley, Anne
Publicado: (2000)

GPR78 promotes lung cancer cell migration and metastasis by activation of Gαq-Rho GTPase pathway
por: Dong, Dan-Dan, et al.
Publicado: (2016)

The Rho GTPase Rnd1 inhibits epithelial–mesenchymal transition in hepatocellular carcinoma and is a favorable anti-metastasis target
por: Qin, Cheng-Dong, et al.
Publicado: (2018)

RHO GTPase family in hepatocellular carcinoma
por: Wang, Tiantian, et al.
Publicado: (2022)

Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases
por: Clark, Edwin A., et al.
Publicado: (1998)

Rho GTPase RhoJ is Associated with Gastric Cancer Progression and Metastasis
por: Kim, Chan, et al.
Publicado: (2016)

Glycolysis regulates pollen tube polarity via Rho GTPase signaling
por: Chen, Wei, et al.
Publicado: (2018)

Role of Rho GTPases in inflammatory bowel disease
por: Li, Xiaoling, et al.
Publicado: (2023)

Extraction of active RhoGTPases by RhoGDI regulates spatiotemporal patterning of RhoGTPases
por: Golding, Adriana E, et al.
Publicado: (2019)

Friend leukemia virus integration 1 activates the Rho GTPase pathway and is associated with metastasis in breast cancer
por: Song, Wei, et al.
Publicado: (2015)

RNA interference targeting human integrin α6 suppresses the metastasis potential of hepatocellular carcinoma cells
por: Lv, Guannan, et al.
Publicado: (2013)

NecroX-5 Can Suppress Melanoma Metastasis by Reducing the Expression of Rho-Family GTPases
por: Moon, Gue-Tae, et al.
Publicado: (2021)

Transcriptomic Dynamics of Active and Inactive States of Rho GTPase MoRho3 in Magnaporthe oryzae
por: Li, Qian, et al.
Publicado: (2022)

Integrins engage mitochondrial function for signal transduction by a mechanism dependent on Rho GTPases
por: Werner, Erica, et al.
Publicado: (2002)

The Rho-Family GTPase Rac1 Regulates Integrin Localization in Drosophila Immunosurveillance Cells
por: Xavier, Miguel J., et al.
Publicado: (2011)

A Small GTPase, RhoA, Inhibits Bacterial Infection Through Integrin Mediated Phagocytosis in Invertebrates
por: Xu, Ji-Dong, et al.
Publicado: (2018)

Rho GTPases: Big Players in Breast Cancer Initiation, Metastasis and Therapeutic Responses
por: Humphries, Brock, et al.
Publicado: (2020)

SNX9 promotes metastasis by enhancing cancer cell invasion via differential regulation of RhoGTPases
por: Bendris, Nawal, et al.
Publicado: (2016)

Function of Rho GTPase Activating Protein 11A in Tumors
por: Zhou, Hui-Nian, et al.
Publicado: (2018)

The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk
por: Arpaia, E, et al.
Publicado: (2012)

The assembly of integrin adhesion complexes requires both extracellular matrix and intracellular rho/rac GTPases
Publicado: (1995)

Rho-GTPase and Atherosclerosis: Pleiotropic Effects of Statins
por: Cai, Anping, et al.
Publicado: (2015)

miR-509 suppresses brain metastasis of breast cancer cells by modulating RhoC and TNF α
por: Xing, Fei, et al.
Publicado: (2015)

Deregulation of Rho GTPases in cancer
por: Porter, Andrew P., et al.
Publicado: (2016)

RhoGTPase in Vascular Disease
por: Strassheim, Derek, et al.
Publicado: (2019)

Rho GTPases in ameloblast differentiation
por: Otsu, Keishi, et al.
Publicado: (2016)

Rho Family GTPases in Cancer
por: Dharmawardhane, Suranganie
Publicado: (2021)

Role of Rho-GTPases in megakaryopoiesis
por: Vainchenker, William, et al.
Publicado: (2021)

Rho GTPases in Model Systems
por: Filić, Vedrana, et al.
Publicado: (2023)

Regulation of Rho GTPases by RhoGDIs in Human Cancers
por: Cho, Hee Jun, et al.
Publicado: (2019)

Rho Family GTPases and Rho GEFs in Glucose Homeostasis
por: Machin, Polly A., et al.
Publicado: (2021)

MMP-9 Signaling Pathways That Engage Rho GTPases in Brain Plasticity
por: Figiel, Izabela, et al.
Publicado: (2021)

YMO1 suppresses invasion and metastasis by inhibiting RhoC signaling and predicts favorable prognosis in hepatocellular carcinoma
por: Chang, Rui-Min, et al.
Publicado: (2016)

Activation of Rho Family GTPases by Small Molecules
por: Palsuledesai, Charuta C., et al.
Publicado: (2018)

RhoA of the Rho Family Small GTPases Is Essential for B Lymphocyte Development
por: Zhang, Shuangmin, et al.
Publicado: (2012)

MicroRNA Regulation of the Small Rho GTPase Regulators—Complexities and Opportunities in Targeting Cancer Metastasis
por: Humphries, Brock A., et al.
Publicado: (2020)

Arf GTPase interplay with Rho GTPases in regulation of the actin cytoskeleton
por: Singh, Vikash, et al.
Publicado: (2017)

Rho GTPase-activating protein 35 suppresses gastric cancer metastasis by regulating cytoskeleton reorganization and epithelial-to-mesenchymal transition
por: Sun, Yi, et al.
Publicado: (2022)

Overexpression of Rhophilin Rho GTPase-binding protein 2 promotes hepatocellular carcinoma
por: Yuan, Bo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_03a3j9aoruf897j1l2ros0es2r