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Transcriptomic analysis and mutational status of IDH1 in paired primary-recurrent intrahepatic cholangiocarcinoma

BACKGROUND: Effective target therapies for intrahepatic cholangiocarcinoma (ICC) have not been identified so far. One of the reasons may be the genetic evolution from primary (PR) to recurrent (REC) tumors. We aim to identify peculiar characteristics and to select potential targets specific for recu...

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Detalles Bibliográficos
Autores principales: Peraldo-Neia, C., Ostano, P., Cavalloni, G., Pignochino, Y., Sangiolo, D., De Cecco, L., Marchesi, E., Ribero, D., Scarpa, A., De Rose, A. M., Giuliani, A., Calise, F., Raggi, C., Invernizzi, P., Aglietta, M., Chiorino, G., Leone, F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989353/
https://www.ncbi.nlm.nih.gov/pubmed/29871612
http://dx.doi.org/10.1186/s12864-018-4829-0