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Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years

BACKGROUND: Junctional ectopic tachycardia is a serious arrhythmia that frequently occurs after tetralogy of Fallot repair. Arrhythmia prophylaxis is not feasible for all pediatric cardiac surgery patients and identification of high risk patients is required. The objectives of this study were to cha...

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Autores principales: Ismail, Mohamed Fouad, Arafat, Amr A., Hamouda, Tamer E., El Tantawy, Amira Esmat, Edrees, Azzahra, Bogis, Abdulbadee, Badawy, Nashwa, Mahmoud, Alaa B., Elmahrouk, Ahmed Farid, Jamjoom, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989382/
https://www.ncbi.nlm.nih.gov/pubmed/29871684
http://dx.doi.org/10.1186/s13019-018-0749-y
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author Ismail, Mohamed Fouad
Arafat, Amr A.
Hamouda, Tamer E.
El Tantawy, Amira Esmat
Edrees, Azzahra
Bogis, Abdulbadee
Badawy, Nashwa
Mahmoud, Alaa B.
Elmahrouk, Ahmed Farid
Jamjoom, Ahmed A.
author_facet Ismail, Mohamed Fouad
Arafat, Amr A.
Hamouda, Tamer E.
El Tantawy, Amira Esmat
Edrees, Azzahra
Bogis, Abdulbadee
Badawy, Nashwa
Mahmoud, Alaa B.
Elmahrouk, Ahmed Farid
Jamjoom, Ahmed A.
author_sort Ismail, Mohamed Fouad
collection PubMed
description BACKGROUND: Junctional ectopic tachycardia is a serious arrhythmia that frequently occurs after tetralogy of Fallot repair. Arrhythmia prophylaxis is not feasible for all pediatric cardiac surgery patients and identification of high risk patients is required. The objectives of this study were to characterize patients with JET, identify its predictors and subsequent complications and the effect of various treatment strategies on the outcomes in selected TOF patients undergoing total repair before 2 years of age. METHODS: From 2003 to 2017, 609 patients had Tetralogy of Fallot repair, 322 were included in our study. We excluded patients above 2 years and patients with preoperative arrhythmia. 29.8% of the patients (n = 96) had postoperative JET. RESULTS: JET patients were younger and had higher preoperative heart rate. Independent predictors of JET were younger age, higher preoperative heart rate, cyanotic spells, non-use of B-blockers and low Mg and Ca (p = 0.011, 0.018, 0.024, 0.001, 0.004 and 0.001; respectively). JET didn’t affect the duration of mechanical ventilation nor hospital stay (p = 0.12 and 0.2 respectively) but prolonged the ICU stay (p = 0.011). JET resolved in 39.5% (n = 38) of patients responding to conventional measures. Amiodarone was used in 31.25% (n = 30) of patients and its use was associated with longer ICU stay (p = 0.017). Ventricular pacing was required in 4 patients (5.2%). Median duration of JET was 30.5 h and 5 patients had recurrent JET episode. Timing of JET onset didn’t affect ICU (p = 0.43) or hospital stay (p = 0.14) however, long duration of JET increased ICU and hospital stay (p = 0.02 and 0.009; respectively). CONCLUSION: JET increases ICU stay after TOF repair. Preoperative B-blockers significantly reduced JET. Patients with preoperative risk factors could benefit from preoperative arrhythmia prophylaxis and aggressive management of postoperative electrolyte disturbance is essential.
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spelling pubmed-59893822018-06-20 Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years Ismail, Mohamed Fouad Arafat, Amr A. Hamouda, Tamer E. El Tantawy, Amira Esmat Edrees, Azzahra Bogis, Abdulbadee Badawy, Nashwa Mahmoud, Alaa B. Elmahrouk, Ahmed Farid Jamjoom, Ahmed A. J Cardiothorac Surg Research Article BACKGROUND: Junctional ectopic tachycardia is a serious arrhythmia that frequently occurs after tetralogy of Fallot repair. Arrhythmia prophylaxis is not feasible for all pediatric cardiac surgery patients and identification of high risk patients is required. The objectives of this study were to characterize patients with JET, identify its predictors and subsequent complications and the effect of various treatment strategies on the outcomes in selected TOF patients undergoing total repair before 2 years of age. METHODS: From 2003 to 2017, 609 patients had Tetralogy of Fallot repair, 322 were included in our study. We excluded patients above 2 years and patients with preoperative arrhythmia. 29.8% of the patients (n = 96) had postoperative JET. RESULTS: JET patients were younger and had higher preoperative heart rate. Independent predictors of JET were younger age, higher preoperative heart rate, cyanotic spells, non-use of B-blockers and low Mg and Ca (p = 0.011, 0.018, 0.024, 0.001, 0.004 and 0.001; respectively). JET didn’t affect the duration of mechanical ventilation nor hospital stay (p = 0.12 and 0.2 respectively) but prolonged the ICU stay (p = 0.011). JET resolved in 39.5% (n = 38) of patients responding to conventional measures. Amiodarone was used in 31.25% (n = 30) of patients and its use was associated with longer ICU stay (p = 0.017). Ventricular pacing was required in 4 patients (5.2%). Median duration of JET was 30.5 h and 5 patients had recurrent JET episode. Timing of JET onset didn’t affect ICU (p = 0.43) or hospital stay (p = 0.14) however, long duration of JET increased ICU and hospital stay (p = 0.02 and 0.009; respectively). CONCLUSION: JET increases ICU stay after TOF repair. Preoperative B-blockers significantly reduced JET. Patients with preoperative risk factors could benefit from preoperative arrhythmia prophylaxis and aggressive management of postoperative electrolyte disturbance is essential. BioMed Central 2018-06-05 /pmc/articles/PMC5989382/ /pubmed/29871684 http://dx.doi.org/10.1186/s13019-018-0749-y Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Ismail, Mohamed Fouad
Arafat, Amr A.
Hamouda, Tamer E.
El Tantawy, Amira Esmat
Edrees, Azzahra
Bogis, Abdulbadee
Badawy, Nashwa
Mahmoud, Alaa B.
Elmahrouk, Ahmed Farid
Jamjoom, Ahmed A.
Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years
title Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years
title_full Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years
title_fullStr Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years
title_full_unstemmed Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years
title_short Junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years
title_sort junctional ectopic tachycardia following tetralogy of fallot repair in children under 2 years
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989382/
https://www.ncbi.nlm.nih.gov/pubmed/29871684
http://dx.doi.org/10.1186/s13019-018-0749-y
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