A survey of microRNA single nucleotide polymorphisms identifies novel breast cancer susceptibility loci in a case-control, population-based study of African-American women

BACKGROUND: MicroRNAs (miRNAs) regulate gene expression and influence cancer. Primary transcripts of miRNAs (pri-miRNAs) are poorly annotated and little is known about the role of germline variation in miRNA genes and breast cancer (BC). We sought to identify germline miRNA variants associated with...

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Detalles Bibliográficos
Autores principales: Bensen, Jeannette T., Graff, Mariaelisa, Young, Kristin L., Sethupathy, Praveen, Parker, Joel, Pecot, Chad V., Currin, Kevin, Haddad, Stephen A., Ruiz-Narváez, Edward A., Haiman, Christopher A., Hong, Chi-Chen, Sucheston-Campbell, Lara E., Zhu, Qianqian, Liu, Song, Yao, Song, Bandera, Elisa V., Rosenberg, Lynn, Lunetta, Kathryn L., Ambrosone, Christine B., Palmer, Julie R., Troester, Melissa A., Olshan, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989404/
https://www.ncbi.nlm.nih.gov/pubmed/29871690
http://dx.doi.org/10.1186/s13058-018-0964-4

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