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Computational modeling of methionine cycle-based metabolism and DNA methylation and the implications for anti-cancer drug response prediction

The relationship between metabolism and methylation is considered to be an important aspect of cancer development and drug efficacy. However, it remains poorly defined how to apply this aspect to improve preclinical disease characterization and clinical treatment outcome. Using available molecular i...

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Detalles Bibliográficos
Autores principales:	Zhang, Mengying, Saad, Christian, Le, Lien, Halfter, Kathrin, Bauer, Bernhard, Mansmann, Ulrich R., Li, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989406/ https://www.ncbi.nlm.nih.gov/pubmed/29875994 http://dx.doi.org/10.18632/oncotarget.24547

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