Performance evaluation of three rapid screening assays for detection of antibodies to hepatitis C virus in Cameroon

OBJECTIVE: This study was aimed at evaluating the performance of three CE-marked rapid diagnostic tests (RDTs): Multisure-HCV, First Response(®) and Toyo(®); for screening anti- HCV antibody using plasma samples. RESULTS: Overall, 200 plasma samples were used. Sensibility and specificity of these RD...

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Detalles Bibliográficos
Autores principales: Fondjo, Clavel Landry Kouam, Ngoupo, Paul Alain Tagnouokam, Ngono, Laure, Plantier, Jean-Christophe, Njouom, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989429/
https://www.ncbi.nlm.nih.gov/pubmed/29871688
http://dx.doi.org/10.1186/s13104-018-3465-8
Descripción
Sumario:OBJECTIVE: This study was aimed at evaluating the performance of three CE-marked rapid diagnostic tests (RDTs): Multisure-HCV, First Response(®) and Toyo(®); for screening anti- HCV antibody using plasma samples. RESULTS: Overall, 200 plasma samples were used. Sensibility and specificity of these RDTs range from 71 to 99 and 78 to 100% respectively. Multisure scored a sensitivity at 99% (95% CI 97–100%) and First Response reached a specificity at 90% (95% CI 85–94.9%). Further studies should be conducted to establish an algorithm using these RTDs for the detection of HCV infection in Cameroon.

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