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In silico identification of drug target pathways in breast cancer subtypes using pathway cross-talk inhibition
BACKGROUND: Despite great development in genome and proteome high-throughput methods, treatment failure is a critical point in the management of most solid cancers, including breast cancer (BC). Multiple alternative mechanisms upon drug treatment are involved to offset therapeutic effects, eventuall...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989433/ https://www.ncbi.nlm.nih.gov/pubmed/29871693 http://dx.doi.org/10.1186/s12967-018-1535-2 |