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In silico identification of drug target pathways in breast cancer subtypes using pathway cross-talk inhibition

BACKGROUND: Despite great development in genome and proteome high-throughput methods, treatment failure is a critical point in the management of most solid cancers, including breast cancer (BC). Multiple alternative mechanisms upon drug treatment are involved to offset therapeutic effects, eventuall...

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Detalles Bibliográficos
Autores principales: Cava, Claudia, Bertoli, Gloria, Castiglioni, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989433/
https://www.ncbi.nlm.nih.gov/pubmed/29871693
http://dx.doi.org/10.1186/s12967-018-1535-2

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