Cargando…

Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana

OBJECTIVE: Anemia, Leukopenia, and thrombocytopenia are commonly observed hematological abnormalities in malaria and typhoid patients. In this study, we evaluated the prevalence of cytopenias in patients with mono-infections of plasmodium parasites (malaria group) or salmonella bacteria (typhoid gro...

Descripción completa

Detalles Bibliográficos
Autores principales: Anabire, Nsoh Godwin, Aryee, Paul Armah, Helegbe, Gideon Kofi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989466/
https://www.ncbi.nlm.nih.gov/pubmed/29871667
http://dx.doi.org/10.1186/s13104-018-3456-9
_version_ 1783329470307893248
author Anabire, Nsoh Godwin
Aryee, Paul Armah
Helegbe, Gideon Kofi
author_facet Anabire, Nsoh Godwin
Aryee, Paul Armah
Helegbe, Gideon Kofi
author_sort Anabire, Nsoh Godwin
collection PubMed
description OBJECTIVE: Anemia, Leukopenia, and thrombocytopenia are commonly observed hematological abnormalities in malaria and typhoid patients. In this study, we evaluated the prevalence of cytopenias in patients with mono-infections of plasmodium parasites (malaria group) or salmonella bacteria (typhoid group). Full blood counts from 79 patients (age ranging from 18 to 77 years) categorized into malaria and typhoid groups at the Tamale Central Hospital were assessed. RESULTS: Data generated were entered and analyzed using SPSS version 20 and Graphpad Prism 6. Values were observed to be significant at p < 0.05. The prevalence of cytopenias were; 29.6, 48.0% for anemia, 38.9, 12.0% for thrombocytopenia, 20.4, 12.0% for leukopenia, 13.0, 8.0% for bicytopenia and 5.6, 4.0% for pancytopenia in both malaria and typhoid groups respectively. Between the two groups of patients, thrombocytopenia was significantly associated with those in the malaria group (χ(2) = 5.84, p < 0.016). No association was found between cytopenias and gender in patients in the malaria group; however, the middle aged group, 36–55 years, was significantly associated with anemia (χ(2) = 12.97, p < 0.002). Cytopenias were not associated with gender, and with different age categories in patients in the typhoid group. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3456-9) contains supplementary material, which is available to authorized users.
format Online
Article
Text
id pubmed-5989466
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-59894662018-06-21 Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana Anabire, Nsoh Godwin Aryee, Paul Armah Helegbe, Gideon Kofi BMC Res Notes Research Note OBJECTIVE: Anemia, Leukopenia, and thrombocytopenia are commonly observed hematological abnormalities in malaria and typhoid patients. In this study, we evaluated the prevalence of cytopenias in patients with mono-infections of plasmodium parasites (malaria group) or salmonella bacteria (typhoid group). Full blood counts from 79 patients (age ranging from 18 to 77 years) categorized into malaria and typhoid groups at the Tamale Central Hospital were assessed. RESULTS: Data generated were entered and analyzed using SPSS version 20 and Graphpad Prism 6. Values were observed to be significant at p < 0.05. The prevalence of cytopenias were; 29.6, 48.0% for anemia, 38.9, 12.0% for thrombocytopenia, 20.4, 12.0% for leukopenia, 13.0, 8.0% for bicytopenia and 5.6, 4.0% for pancytopenia in both malaria and typhoid groups respectively. Between the two groups of patients, thrombocytopenia was significantly associated with those in the malaria group (χ(2) = 5.84, p < 0.016). No association was found between cytopenias and gender in patients in the malaria group; however, the middle aged group, 36–55 years, was significantly associated with anemia (χ(2) = 12.97, p < 0.002). Cytopenias were not associated with gender, and with different age categories in patients in the typhoid group. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3456-9) contains supplementary material, which is available to authorized users. BioMed Central 2018-06-05 /pmc/articles/PMC5989466/ /pubmed/29871667 http://dx.doi.org/10.1186/s13104-018-3456-9 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
Anabire, Nsoh Godwin
Aryee, Paul Armah
Helegbe, Gideon Kofi
Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana
title Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana
title_full Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana
title_fullStr Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana
title_full_unstemmed Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana
title_short Hematological abnormalities in patients with malaria and typhoid in Tamale Metropolis of Ghana
title_sort hematological abnormalities in patients with malaria and typhoid in tamale metropolis of ghana
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989466/
https://www.ncbi.nlm.nih.gov/pubmed/29871667
http://dx.doi.org/10.1186/s13104-018-3456-9
work_keys_str_mv AT anabirensohgodwin hematologicalabnormalitiesinpatientswithmalariaandtyphoidintamalemetropolisofghana
AT aryeepaularmah hematologicalabnormalitiesinpatientswithmalariaandtyphoidintamalemetropolisofghana
AT helegbegideonkofi hematologicalabnormalitiesinpatientswithmalariaandtyphoidintamalemetropolisofghana