B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma

Primary central nervous system lymphoma (PCNSL) is an uncommon tumor in the brain. Although most PCNSL are readily diagnosed as diffuse large B cell lymphoma (DLBCL) on the first biopsy, very rare cases have been described in which the first detected intracerebral lesions are non-neoplastic, and are...

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Autores principales: Javier, Rodrigo, Shaikh, Nawal, Lesniak, Maciej S., Sonabend, Adam, Stupp, Roger, Behdad, Amir, Horbinski, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989478/
https://www.ncbi.nlm.nih.gov/pubmed/29871654
http://dx.doi.org/10.1186/s13000-018-0717-9
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author Javier, Rodrigo
Shaikh, Nawal
Lesniak, Maciej S.
Sonabend, Adam
Stupp, Roger
Behdad, Amir
Horbinski, Craig
author_facet Javier, Rodrigo
Shaikh, Nawal
Lesniak, Maciej S.
Sonabend, Adam
Stupp, Roger
Behdad, Amir
Horbinski, Craig
author_sort Javier, Rodrigo
collection PubMed
description Primary central nervous system lymphoma (PCNSL) is an uncommon tumor in the brain. Although most PCNSL are readily diagnosed as diffuse large B cell lymphoma (DLBCL) on the first biopsy, very rare cases have been described in which the first detected intracerebral lesions are non-neoplastic, and are composed mostly of perivascular T cells, not B cells. This phenomenon is known as “sentinel lesions.”
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spelling pubmed-59894782018-06-21 B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma Javier, Rodrigo Shaikh, Nawal Lesniak, Maciej S. Sonabend, Adam Stupp, Roger Behdad, Amir Horbinski, Craig Diagn Pathol Case Report Primary central nervous system lymphoma (PCNSL) is an uncommon tumor in the brain. Although most PCNSL are readily diagnosed as diffuse large B cell lymphoma (DLBCL) on the first biopsy, very rare cases have been described in which the first detected intracerebral lesions are non-neoplastic, and are composed mostly of perivascular T cells, not B cells. This phenomenon is known as “sentinel lesions.” BioMed Central 2018-06-05 /pmc/articles/PMC5989478/ /pubmed/29871654 http://dx.doi.org/10.1186/s13000-018-0717-9 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Javier, Rodrigo
Shaikh, Nawal
Lesniak, Maciej S.
Sonabend, Adam
Stupp, Roger
Behdad, Amir
Horbinski, Craig
B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma
title B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma
title_full B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma
title_fullStr B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma
title_full_unstemmed B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma
title_short B cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma
title_sort b cell-rich non-neoplastic sentinel lesion preceding primary central nervous system lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989478/
https://www.ncbi.nlm.nih.gov/pubmed/29871654
http://dx.doi.org/10.1186/s13000-018-0717-9
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