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Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design

BACKGROUND: Bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%–2% of the general population. It is associated not only with notable valvular risk (aortic stenosis and/or regurgitation, endocarditis) but also with aortopathy with a wide spectrum of unpredictable c...

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Autores principales: Citro, Rodolfo, Cecconi, Moreno, La Carrubba, Salvatore, Bossone, Eduardo, Antonini-Canterin, Francesco, Nistri, Stefano, Chirillo, Fabio, Dentamaro, Ilaria, Bellino, Michele, Posteraro, Alfredo, Giorgi, Mauro, Petrella, Licia, Monte, Ines, Manuppelli, Vincenzo, Mantero, Antonio, Carerj, Scipione, Benedetto, Frank, Colonna, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989554/
https://www.ncbi.nlm.nih.gov/pubmed/29911003
http://dx.doi.org/10.4103/jcecho.jcecho_5_18
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author Citro, Rodolfo
Cecconi, Moreno
La Carrubba, Salvatore
Bossone, Eduardo
Antonini-Canterin, Francesco
Nistri, Stefano
Chirillo, Fabio
Dentamaro, Ilaria
Bellino, Michele
Posteraro, Alfredo
Giorgi, Mauro
Petrella, Licia
Monte, Ines
Manuppelli, Vincenzo
Mantero, Antonio
Carerj, Scipione
Benedetto, Frank
Colonna, Paolo
author_facet Citro, Rodolfo
Cecconi, Moreno
La Carrubba, Salvatore
Bossone, Eduardo
Antonini-Canterin, Francesco
Nistri, Stefano
Chirillo, Fabio
Dentamaro, Ilaria
Bellino, Michele
Posteraro, Alfredo
Giorgi, Mauro
Petrella, Licia
Monte, Ines
Manuppelli, Vincenzo
Mantero, Antonio
Carerj, Scipione
Benedetto, Frank
Colonna, Paolo
author_sort Citro, Rodolfo
collection PubMed
description BACKGROUND: Bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%–2% of the general population. It is associated not only with notable valvular risk (aortic stenosis and/or regurgitation, endocarditis) but also with aortopathy with a wide spectrum of unpredictable clinical presentations, including aneurysmal dilation of the aortic root and/or ascending thoracic aorta, isthmic coarctation, aortic dissection, or wall rupture. METHODS: The REgistro della Valvola Aortica Bicuspide della Società Italiana di ECocardiografia e CArdiovascular Imaging is a retrospective (from January 1, 2010)/prospective, multicenter, observational registry, expected to enroll 3000 patients with definitive diagnosis of BAV made by transthoracic and/or transesophageal echocardiography, computed tomography, cardiovascular magnetic resonance, or at surgery. Inclusion criteria were definitive diagnosis of BAV. Patients will be enrolled regardless of the presence and severity of aortic valve dysfunction or aortic vessel disease and the coexistence of other congenital cardiovascular malformations. Exclusion criteria were uncertain BAV diagnosis, impossibility of obtaining informed consent, inability to carry out the follow-up. Anamnestic, demographic, clinical, and instrumental data collected both at first evaluation and during follow-up will be integrated into dedicated software. The aim is to derive a data set of unselected BAV patients with the main purpose of assessing the current clinical presentation, management, and outcomes of BAV. CONCLUSIONS: A multicenter registry covering a large population of BAV patients could have a profound impact on the understanding of the natural history of this disease and could influence its management.
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spelling pubmed-59895542018-06-15 Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design Citro, Rodolfo Cecconi, Moreno La Carrubba, Salvatore Bossone, Eduardo Antonini-Canterin, Francesco Nistri, Stefano Chirillo, Fabio Dentamaro, Ilaria Bellino, Michele Posteraro, Alfredo Giorgi, Mauro Petrella, Licia Monte, Ines Manuppelli, Vincenzo Mantero, Antonio Carerj, Scipione Benedetto, Frank Colonna, Paolo J Cardiovasc Echogr Registry of Italian Society of Echocardiography and Cardiovascular Imaging BACKGROUND: Bicuspid aortic valve (BAV) is the most common congenital heart disease, affecting 0.5%–2% of the general population. It is associated not only with notable valvular risk (aortic stenosis and/or regurgitation, endocarditis) but also with aortopathy with a wide spectrum of unpredictable clinical presentations, including aneurysmal dilation of the aortic root and/or ascending thoracic aorta, isthmic coarctation, aortic dissection, or wall rupture. METHODS: The REgistro della Valvola Aortica Bicuspide della Società Italiana di ECocardiografia e CArdiovascular Imaging is a retrospective (from January 1, 2010)/prospective, multicenter, observational registry, expected to enroll 3000 patients with definitive diagnosis of BAV made by transthoracic and/or transesophageal echocardiography, computed tomography, cardiovascular magnetic resonance, or at surgery. Inclusion criteria were definitive diagnosis of BAV. Patients will be enrolled regardless of the presence and severity of aortic valve dysfunction or aortic vessel disease and the coexistence of other congenital cardiovascular malformations. Exclusion criteria were uncertain BAV diagnosis, impossibility of obtaining informed consent, inability to carry out the follow-up. Anamnestic, demographic, clinical, and instrumental data collected both at first evaluation and during follow-up will be integrated into dedicated software. The aim is to derive a data set of unselected BAV patients with the main purpose of assessing the current clinical presentation, management, and outcomes of BAV. CONCLUSIONS: A multicenter registry covering a large population of BAV patients could have a profound impact on the understanding of the natural history of this disease and could influence its management. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5989554/ /pubmed/29911003 http://dx.doi.org/10.4103/jcecho.jcecho_5_18 Text en Copyright: © 2018 Journal of Cardiovascular Echography http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Registry of Italian Society of Echocardiography and Cardiovascular Imaging
Citro, Rodolfo
Cecconi, Moreno
La Carrubba, Salvatore
Bossone, Eduardo
Antonini-Canterin, Francesco
Nistri, Stefano
Chirillo, Fabio
Dentamaro, Ilaria
Bellino, Michele
Posteraro, Alfredo
Giorgi, Mauro
Petrella, Licia
Monte, Ines
Manuppelli, Vincenzo
Mantero, Antonio
Carerj, Scipione
Benedetto, Frank
Colonna, Paolo
Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design
title Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design
title_full Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design
title_fullStr Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design
title_full_unstemmed Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design
title_short Bicuspid Aortic Valve Registry of the Italian Society of Echocardiography and Cardiovascular Imaging (REgistro della valvola aortica bicuspide della società italiana di ECocardiografia e CArdiovascular imaging): Rationale and Study Design
title_sort bicuspid aortic valve registry of the italian society of echocardiography and cardiovascular imaging (registro della valvola aortica bicuspide della società italiana di ecocardiografia e cardiovascular imaging): rationale and study design
topic Registry of Italian Society of Echocardiography and Cardiovascular Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989554/
https://www.ncbi.nlm.nih.gov/pubmed/29911003
http://dx.doi.org/10.4103/jcecho.jcecho_5_18
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