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FGF2 Has Distinct Molecular Functions from GDNF in the Mouse Germline Niche

Both glial cell line-derived neurotrophic factor (GDNF) and fibroblast growth factor 2 (FGF2) are bona fide self-renewal factors for spermatogonial stem cells, whereas retinoic acid (RA) induces spermatogonial differentiation. In this study, we investigated the functional differences between FGF2 an...

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Detalles Bibliográficos
Autores principales: Masaki, Kaito, Sakai, Mizuki, Kuroki, Shunsuke, Jo, Jun-Ichiro, Hoshina, Kazuo, Fujimori, Yuki, Oka, Kenji, Amano, Toshiyasu, Yamanaka, Takahiro, Tachibana, Makoto, Tabata, Yasuhiko, Shiozawa, Tanri, Ishizuka, Osamu, Hochi, Shinichi, Takashima, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989648/
https://www.ncbi.nlm.nih.gov/pubmed/29681540
http://dx.doi.org/10.1016/j.stemcr.2018.03.016