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Unraveling the Inconsistencies of Cardiac Differentiation Efficiency Induced by the GSK3β Inhibitor CHIR99021 in Human Pluripotent Stem Cells
Cardiac differentiation efficiency is hampered by inconsistencies and low reproducibility. We analyzed the differentiation process of multiple human pluripotent stem cell (hPSC) lines in response to dynamic GSK3β inhibition under varying cell culture conditions. hPSCs showed strong differences in ce...
Autores principales: | Laco, Filip, Woo, Tsung Liang, Zhong, Qixing, Szmyd, Radoslaw, Ting, Sherwin, Khan, Fahima Jaleel, Chai, Christina L.L., Reuveny, Shaul, Chen, Allen, Oh, Steve |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989659/ https://www.ncbi.nlm.nih.gov/pubmed/29706502 http://dx.doi.org/10.1016/j.stemcr.2018.03.023 |
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