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Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells
Trophic factor delivery to the brain using stem cell-derived neural progenitors is a powerful way to bypass the blood-brain barrier. Protection of diseased neurons using this technology is a promising therapy for neurodegenerative diseases. Glial cell line-derived neurotrophic factor (GDNF) has prov...
Autores principales: | Akhtar, Aslam Abbasi, Gowing, Genevieve, Kobritz, Naomi, Savinoff, Steve E., Garcia, Leslie, Saxon, David, Cho, Noell, Kim, Gibum, Tom, Colton M., Park, Hannah, Lawless, George, Shelley, Brandon C., Mattis, Virginia B., Breunig, Joshua J., Svendsen, Clive N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989694/ https://www.ncbi.nlm.nih.gov/pubmed/29706501 http://dx.doi.org/10.1016/j.stemcr.2018.03.024 |
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