Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress

Nakajo-Nishimura syndrome (NNS) is an immunoproteasome-associated autoinflammatory disorder caused by a mutation of the PSMB8 gene. Although dysfunction of the immunoproteasome causes various cellular stresses attributed to the overproduction of inflammatory cytokines and chemokines in NNS, the unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Honda-Ozaki, Fumiko, Terashima, Madoka, Niwa, Akira, Saiki, Norikazu, Kawasaki, Yuri, Ito, Haruna, Hotta, Akitsu, Nagahashi, Ayako, Igura, Koichi, Asaka, Isao, Li, Hongmei Lisa, Yanagimachi, Masakatsu, Furukawa, Fukumi, Kanazawa, Nobuo, Nakahata, Tatsutoshi, Saito, Megumu K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989695/
https://www.ncbi.nlm.nih.gov/pubmed/29731430
http://dx.doi.org/10.1016/j.stemcr.2018.04.004

Ejemplares similares

Ejemplares similares