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Rho‐kinase inhibitors do not expand hematoma volume in acute experimental intracerebral hemorrhage

Rho‐associated kinase (ROCK) is an emerging target in acute ischemic stroke. Early pre‐hospital treatment with ROCK inhibitors may improve their efficacy, but their antithrombotic effects raise safety concerns in hemorrhagic stroke, precluding use prior to neuroimaging. Therefore, we tested whether...

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Detalles Bibliográficos
Autores principales: Akhter, Murtaza, Qin, Tom, Fischer, Paul, Sadeghian, Homa, Kim, Hyung Hwan, Whalen, Michael J., Goldstein, Joshua N., Ayata, Cenk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989779/
https://www.ncbi.nlm.nih.gov/pubmed/29928660
http://dx.doi.org/10.1002/acn3.569