Cargando…

Surface-enhanced Raman nanoparticles for tumor theranostics applications

Raman spectroscopy, amplified by surface-enhanced Raman scattering (SERS) nanoparticles, can provide an in vivo imaging modality due to its high molecular specificity, high sensitivity, and negligible autofluorescence. The basis, composition, and methodologies developed for SERS nanoparticles are he...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yangyang, Wei, Qiaolin, Ma, Fei, Li, Xin, Liu, Fengyong, Zhou, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989827/
https://www.ncbi.nlm.nih.gov/pubmed/29881674
http://dx.doi.org/10.1016/j.apsb.2018.03.007
_version_ 1783329525386444800
author Li, Yangyang
Wei, Qiaolin
Ma, Fei
Li, Xin
Liu, Fengyong
Zhou, Min
author_facet Li, Yangyang
Wei, Qiaolin
Ma, Fei
Li, Xin
Liu, Fengyong
Zhou, Min
author_sort Li, Yangyang
collection PubMed
description Raman spectroscopy, amplified by surface-enhanced Raman scattering (SERS) nanoparticles, can provide an in vivo imaging modality due to its high molecular specificity, high sensitivity, and negligible autofluorescence. The basis, composition, and methodologies developed for SERS nanoparticles are herein described. The research hotspots that are the focus in this paper are tumor imaging-guided theranostics and biosensing. The next breakthrough may be the development of biocompatible SERS nanoparticles and spectroscopic devices for clinical applications.
format Online
Article
Text
id pubmed-5989827
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-59898272018-06-07 Surface-enhanced Raman nanoparticles for tumor theranostics applications Li, Yangyang Wei, Qiaolin Ma, Fei Li, Xin Liu, Fengyong Zhou, Min Acta Pharm Sin B Review Raman spectroscopy, amplified by surface-enhanced Raman scattering (SERS) nanoparticles, can provide an in vivo imaging modality due to its high molecular specificity, high sensitivity, and negligible autofluorescence. The basis, composition, and methodologies developed for SERS nanoparticles are herein described. The research hotspots that are the focus in this paper are tumor imaging-guided theranostics and biosensing. The next breakthrough may be the development of biocompatible SERS nanoparticles and spectroscopic devices for clinical applications. Elsevier 2018-05 2018-03-26 /pmc/articles/PMC5989827/ /pubmed/29881674 http://dx.doi.org/10.1016/j.apsb.2018.03.007 Text en © 2018 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Review
Li, Yangyang
Wei, Qiaolin
Ma, Fei
Li, Xin
Liu, Fengyong
Zhou, Min
Surface-enhanced Raman nanoparticles for tumor theranostics applications
title Surface-enhanced Raman nanoparticles for tumor theranostics applications
title_full Surface-enhanced Raman nanoparticles for tumor theranostics applications
title_fullStr Surface-enhanced Raman nanoparticles for tumor theranostics applications
title_full_unstemmed Surface-enhanced Raman nanoparticles for tumor theranostics applications
title_short Surface-enhanced Raman nanoparticles for tumor theranostics applications
title_sort surface-enhanced raman nanoparticles for tumor theranostics applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989827/
https://www.ncbi.nlm.nih.gov/pubmed/29881674
http://dx.doi.org/10.1016/j.apsb.2018.03.007
work_keys_str_mv AT liyangyang surfaceenhancedramannanoparticlesfortumortheranosticsapplications
AT weiqiaolin surfaceenhancedramannanoparticlesfortumortheranosticsapplications
AT mafei surfaceenhancedramannanoparticlesfortumortheranosticsapplications
AT lixin surfaceenhancedramannanoparticlesfortumortheranosticsapplications
AT liufengyong surfaceenhancedramannanoparticlesfortumortheranosticsapplications
AT zhoumin surfaceenhancedramannanoparticlesfortumortheranosticsapplications