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Odd‐skipped related 1 inhibits lung cancer proliferation and invasion by reducing Wnt signaling through the suppression of SOX9 and β‐catenin

The odd‐skipped related 1 (OSR1) gene encodes a zinc‐finger transcription factor. The expression and significance of OSR1 in human tumors remains unclear. We found that OSR1 was downregulated in lung cancers, and its expression was correlated with poor differentiation. Overexpression of OSR1 by OSR1...

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Detalles Bibliográficos
Autores principales: Wang, Yuan, Lei, Lei, Zheng, Yi‐Wen, Zhang, Li, Li, Zhi‐Han, Shen, Hao‐Yue, Jiang, Gui‐Yang, Zhang, Xiu‐Peng, Wang, En‐Hua, Xu, Hong‐Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989870/
https://www.ncbi.nlm.nih.gov/pubmed/29660200
http://dx.doi.org/10.1111/cas.13614