Evaluating the contribution of genetic and familial shared environment to common disease using the UK Biobank

Genome-wide association studies have detected many loci underlying susceptibility to disease, but most of the genetic factors that contribute to disease susceptibility remain unknown. Here we provide evidence that part of the missing heritability can be explained by an overestimation of heritability...

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Detalles Bibliográficos
Autores principales: Muñoz, María, Pong-Wong, Ricardo, Canela-Xandri, Oriol, Rawlik, Konrad, Haley, Chris S., Tenesa, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989924/
https://www.ncbi.nlm.nih.gov/pubmed/27428752
http://dx.doi.org/10.1038/ng.3618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989924/
https://www.ncbi.nlm.nih.gov/pubmed/27428752
http://dx.doi.org/10.1038/ng.3618

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