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Risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias

BACKGROUND: Delayed gastric emptying can complicate surgery for hiatus hernia. The aim of this study was to quantify its incidence following laparoscopic repair of very large hiatus hernias, identify key risk factors for its occurrence and determine its impact on clinical outcomes. METHODS: Data col...

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Autores principales: Tog, C., Liu, D. S., Lim, H. K., Stiven, P., Thompson, S. K., Watson, D. I., Aly, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989959/
https://www.ncbi.nlm.nih.gov/pubmed/29951609
http://dx.doi.org/10.1002/bjs5.11
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author Tog, C.
Liu, D. S.
Lim, H. K.
Stiven, P.
Thompson, S. K.
Watson, D. I.
Aly, A.
author_facet Tog, C.
Liu, D. S.
Lim, H. K.
Stiven, P.
Thompson, S. K.
Watson, D. I.
Aly, A.
author_sort Tog, C.
collection PubMed
description BACKGROUND: Delayed gastric emptying can complicate surgery for hiatus hernia. The aim of this study was to quantify its incidence following laparoscopic repair of very large hiatus hernias, identify key risk factors for its occurrence and determine its impact on clinical outcomes. METHODS: Data collected from a randomized trial of patients who underwent laparoscopic mesh versus sutured repair of very large hiatus hernias (more than 50 per cent of stomach in chest) were analysed retrospectively. Delayed gastric emptying was defined as endoscopic evidence of solid food in the stomach after fasting for 6 h at 6 months after surgery. RESULTS: Delayed gastric emptying occurred in 19 of 102 patients (18·6 per cent). In univariable analysis, type 2 paraoesophageal hernia (relative risk (RR) 3·15, 95 per cent c.i. 1·41 to 7·06), concurrent anterior and posterior hiatal repair (RR 2·66, 1·14 to 6·18), hernia sac excision (RR 4·85, 1·65 to 14·24), 270°/360° fundoplication (RR 3·64, 1·72 to 7·68), division of short gastric vessels (RR 6·82, 2·12 to 21·90) and revisional surgery (RR 3·69, 1·73 to 7·87) correlated with delayed gastric emptying. In multivariable analysis, division of short gastric vessels (RR 6·27, 1·85 to 21·26) and revisional surgery (RR 6·19, 1·32 to 28·96) were independently associated with delayed gastric emptying. Delayed gastric emptying correlated with adverse gastrointestinal symptomatology, including higher rates of bloating, nausea, vomiting and anorexia, as well as reduced patient satisfaction with the operation and recovery. CONCLUSION: Delayed gastric emptying following large hiatus hernia repair is common and associated with adverse symptoms and reduced patient satisfaction. Division of short gastric vessels and revisional surgery were independently associated with its occurrence.
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spelling pubmed-59899592018-06-27 Risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias Tog, C. Liu, D. S. Lim, H. K. Stiven, P. Thompson, S. K. Watson, D. I. Aly, A. BJS Open Original Articles BACKGROUND: Delayed gastric emptying can complicate surgery for hiatus hernia. The aim of this study was to quantify its incidence following laparoscopic repair of very large hiatus hernias, identify key risk factors for its occurrence and determine its impact on clinical outcomes. METHODS: Data collected from a randomized trial of patients who underwent laparoscopic mesh versus sutured repair of very large hiatus hernias (more than 50 per cent of stomach in chest) were analysed retrospectively. Delayed gastric emptying was defined as endoscopic evidence of solid food in the stomach after fasting for 6 h at 6 months after surgery. RESULTS: Delayed gastric emptying occurred in 19 of 102 patients (18·6 per cent). In univariable analysis, type 2 paraoesophageal hernia (relative risk (RR) 3·15, 95 per cent c.i. 1·41 to 7·06), concurrent anterior and posterior hiatal repair (RR 2·66, 1·14 to 6·18), hernia sac excision (RR 4·85, 1·65 to 14·24), 270°/360° fundoplication (RR 3·64, 1·72 to 7·68), division of short gastric vessels (RR 6·82, 2·12 to 21·90) and revisional surgery (RR 3·69, 1·73 to 7·87) correlated with delayed gastric emptying. In multivariable analysis, division of short gastric vessels (RR 6·27, 1·85 to 21·26) and revisional surgery (RR 6·19, 1·32 to 28·96) were independently associated with delayed gastric emptying. Delayed gastric emptying correlated with adverse gastrointestinal symptomatology, including higher rates of bloating, nausea, vomiting and anorexia, as well as reduced patient satisfaction with the operation and recovery. CONCLUSION: Delayed gastric emptying following large hiatus hernia repair is common and associated with adverse symptoms and reduced patient satisfaction. Division of short gastric vessels and revisional surgery were independently associated with its occurrence. John Wiley & Sons, Ltd 2017-08-28 /pmc/articles/PMC5989959/ /pubmed/29951609 http://dx.doi.org/10.1002/bjs5.11 Text en © 2017 The Authors. BJS Open published by John Wiley & Sons Ltd on behalf of BJS Society Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Tog, C.
Liu, D. S.
Lim, H. K.
Stiven, P.
Thompson, S. K.
Watson, D. I.
Aly, A.
Risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias
title Risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias
title_full Risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias
title_fullStr Risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias
title_full_unstemmed Risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias
title_short Risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias
title_sort risk factors for delayed gastric emptying following laparoscopic repair of very large hiatus hernias
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989959/
https://www.ncbi.nlm.nih.gov/pubmed/29951609
http://dx.doi.org/10.1002/bjs5.11
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