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Common and unique transcriptional responses to dietary restriction and loss of insulin receptor substrate 1 (IRS1) in mice

Dietary restriction (DR) is the most widely studied non-genetic intervention capable of extending lifespan across multiple taxa. Modulation of genes, primarily within the insulin/insulin-like growth factor signalling (IIS) and the mechanistic target of rapamycin (mTOR) signalling pathways also act t...

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Detalles Bibliográficos
Autores principales:	Page, Melissa M., Schuster, Eugene F., Mudaliar, Manikhandan, Herzyk, Pawel, Withers, Dominic J., Selman, Colin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990393/ https://www.ncbi.nlm.nih.gov/pubmed/29779018 http://dx.doi.org/10.18632/aging.101446

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