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Recurrent Risk of Preterm Birth in the Third Pregnancy in Korea

BACKGROUND: Although preterm delivery is the most common cause of infant morbidity and mortality, an obvious cause cannot be found in most cases. Preterm delivery is known to be the most important risk factor for preterm birth in a subsequent pregnancy. We aimed to evaluate the recurrence rate of pr...

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Autores principales: Ouh, Yung-Taek, Park, Jong Heon, Ahn, Ki Hoon, Hong, Soon-Cheol, Oh, Min-Jeong, Kim, Hai-Joong, Han, Sung Won, Cho, Geum Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990443/
https://www.ncbi.nlm.nih.gov/pubmed/29892210
http://dx.doi.org/10.3346/jkms.2018.33.e170
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author Ouh, Yung-Taek
Park, Jong Heon
Ahn, Ki Hoon
Hong, Soon-Cheol
Oh, Min-Jeong
Kim, Hai-Joong
Han, Sung Won
Cho, Geum Joon
author_facet Ouh, Yung-Taek
Park, Jong Heon
Ahn, Ki Hoon
Hong, Soon-Cheol
Oh, Min-Jeong
Kim, Hai-Joong
Han, Sung Won
Cho, Geum Joon
author_sort Ouh, Yung-Taek
collection PubMed
description BACKGROUND: Although preterm delivery is the most common cause of infant morbidity and mortality, an obvious cause cannot be found in most cases. Preterm delivery is known to be the most important risk factor for preterm birth in a subsequent pregnancy. We aimed to evaluate the recurrence rate of premature births for subsequent pregnancies in women with a history of a preterm birth. METHODS: Study data were collected from the Korea National Health Insurance (KNHI) claims database and data from a national health-screening program for infants and children. We enrolled women who had their first delivery between January 1, 2007 and December 31, 2007 and a subsequent delivery before 2014. RESULTS: Preterm delivery had a significant higher risk of preterm birth in a subsequent singleton pregnancy. The risk of preterm birth at second pregnancy was 2.2% in women whose first delivery at ≥ 37 weeks and 18.6% in women whose first delivery at < 37 weeks (relative risks [RR], 8.64; 95% confidence interval [CI], 7.94–9.40). In the analysis of the third pregnancy, we compared women with an initial term birth followed by preterm birth and women with an initial preterm birth followed by a subsequent term birth. A history of a just preceding preterm birth at < 37 weeks was the most relevant factor for recurrence of preterm delivery in a subsequent pregnancy (26.6%, RR, 4.01; 95% CI, 2.45–6.58). CONCLUSION: We found that the prognosis of a third pregnancy was more closely related to the outcome of the second pregnancy to that of the first pregnancy.
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spelling pubmed-59904432018-06-12 Recurrent Risk of Preterm Birth in the Third Pregnancy in Korea Ouh, Yung-Taek Park, Jong Heon Ahn, Ki Hoon Hong, Soon-Cheol Oh, Min-Jeong Kim, Hai-Joong Han, Sung Won Cho, Geum Joon J Korean Med Sci Original Article BACKGROUND: Although preterm delivery is the most common cause of infant morbidity and mortality, an obvious cause cannot be found in most cases. Preterm delivery is known to be the most important risk factor for preterm birth in a subsequent pregnancy. We aimed to evaluate the recurrence rate of premature births for subsequent pregnancies in women with a history of a preterm birth. METHODS: Study data were collected from the Korea National Health Insurance (KNHI) claims database and data from a national health-screening program for infants and children. We enrolled women who had their first delivery between January 1, 2007 and December 31, 2007 and a subsequent delivery before 2014. RESULTS: Preterm delivery had a significant higher risk of preterm birth in a subsequent singleton pregnancy. The risk of preterm birth at second pregnancy was 2.2% in women whose first delivery at ≥ 37 weeks and 18.6% in women whose first delivery at < 37 weeks (relative risks [RR], 8.64; 95% confidence interval [CI], 7.94–9.40). In the analysis of the third pregnancy, we compared women with an initial term birth followed by preterm birth and women with an initial preterm birth followed by a subsequent term birth. A history of a just preceding preterm birth at < 37 weeks was the most relevant factor for recurrence of preterm delivery in a subsequent pregnancy (26.6%, RR, 4.01; 95% CI, 2.45–6.58). CONCLUSION: We found that the prognosis of a third pregnancy was more closely related to the outcome of the second pregnancy to that of the first pregnancy. The Korean Academy of Medical Sciences 2018-05-11 /pmc/articles/PMC5990443/ /pubmed/29892210 http://dx.doi.org/10.3346/jkms.2018.33.e170 Text en © 2018 The Korean Academy of Medical Sciences. https://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ouh, Yung-Taek
Park, Jong Heon
Ahn, Ki Hoon
Hong, Soon-Cheol
Oh, Min-Jeong
Kim, Hai-Joong
Han, Sung Won
Cho, Geum Joon
Recurrent Risk of Preterm Birth in the Third Pregnancy in Korea
title Recurrent Risk of Preterm Birth in the Third Pregnancy in Korea
title_full Recurrent Risk of Preterm Birth in the Third Pregnancy in Korea
title_fullStr Recurrent Risk of Preterm Birth in the Third Pregnancy in Korea
title_full_unstemmed Recurrent Risk of Preterm Birth in the Third Pregnancy in Korea
title_short Recurrent Risk of Preterm Birth in the Third Pregnancy in Korea
title_sort recurrent risk of preterm birth in the third pregnancy in korea
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990443/
https://www.ncbi.nlm.nih.gov/pubmed/29892210
http://dx.doi.org/10.3346/jkms.2018.33.e170
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