ATX-MS-1467 Induces Long-Term Tolerance to Myelin Basic Protein in (DR2 × Ob1)F1 Mice by Induction of IL-10-Secreting iTregs

INTRODUCTION: Antigen-specific immunotherapy could provide a targeted approach for the treatment of multiple sclerosis that removes the need for broad-acting immunomodulatory drugs. ATX-MS-1467 is a mixture of four peptides identified as the main immune-dominant disease-associated T-cell epitopes in...

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Detalles Bibliográficos
Autores principales: De Souza, Adriano Luís Soares, Rudin, Stefan, Chang, Rui, Mitchell, Keith, Crandall, Timothy, Huang, Shuning, Choi, Ji-Kyung, Okitsu, Shinji L., Graham, Danielle L., Tomkinson, Blake, Dellovade, Tammy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990509/
https://www.ncbi.nlm.nih.gov/pubmed/29542041
http://dx.doi.org/10.1007/s40120-018-0094-z

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