Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia

Next-generation sequencing has provided a detailed overview of the various genomic lesions implicated in the pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL). Typically, 10–20 protein-altering lesions are found in T-ALL cells at diagnosis. However, it is currently unclear in which order t...

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Detalles Bibliográficos
Autores principales: De Bie, Jolien, Demeyer, Sofie, Alberti-Servera, Llucia, Geerdens, Ellen, Segers, Heidi, Broux, Michaël, De Keersmaecker, Kim, Michaux, Lucienne, Vandenberghe, Peter, Voet, Thierry, Boeckx, Nancy, Uyttebroeck, Anne, Cools, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990522/
https://www.ncbi.nlm.nih.gov/pubmed/29740158
http://dx.doi.org/10.1038/s41375-018-0127-8

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