Compound CAR T-cells as a double-pronged approach for treating acute myeloid leukemia

Acute myeloid leukemia (AML) bears heterogeneous cells that can consequently offset killing by single-CAR-based therapy, which results in disease relapse. Leukemic stem cells (LSCs) associated with CD123 expression comprise a rare population that also plays an important role in disease progression a...

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Detalles Bibliográficos
Autores principales: Petrov, Jessica C., Wada, Masayuki, Pinz, Kevin G., Yan, Lulu E., Chen, Kevin H., Shuai, Xiao, Liu, Hua, Chen, Xi, Leung, Lai-Han, Salman, Huda, Hagag, Nabil, Liu, Fang, Jiang, Xun, Ma, Yupo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990523/
https://www.ncbi.nlm.nih.gov/pubmed/29515236
http://dx.doi.org/10.1038/s41375-018-0075-3

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