Cargando…
Anticalin(®) Proteins as Therapeutic Agents in Human Diseases
Anticalin proteins are an emerging class of clinical-stage biopharmaceuticals with high potential as an alternative to antibodies. Anticalin molecules are generated by combinatorial design from natural lipocalins, which are abundant plasma proteins in humans, and reveal a simple, compact fold domina...
Autores principales: | Rothe, Christine, Skerra, Arne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990566/ https://www.ncbi.nlm.nih.gov/pubmed/29748739 http://dx.doi.org/10.1007/s40259-018-0278-1 |
Ejemplares similares
-
Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice
por: Deuschle, Friedrich‐Christian, et al.
Publicado: (2020) -
Structural plasticity in the loop region of engineered lipocalins with novel ligand specificities, so-called Anticalins
por: Achatz, S., et al.
Publicado: (2021) -
High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer β-amyloid peptide
por: Rauth, Sabine, et al.
Publicado: (2016) -
Structure of the human heterodimeric transporter 4F2hc-LAT2 in complex with Anticalin, an alternative binding protein for applications in single-particle cryo-EM
por: Jeckelmann, Jean-Marc, et al.
Publicado: (2022) -
Development of a high affinity Anticalin(®) directed against human CD98hc for theranostic applications
por: Deuschle, Friedrich-Christian, et al.
Publicado: (2020)