Cargando…

Retinoic Acid Receptor-Related Orphan Receptors: Critical Roles in Tumorigenesis

Retinoic acid receptor-related orphan receptors (RORs) include RORα (NR1F1), RORβ (NR1F2), and RORγ (NR1F3). These receptors are reported to activate transcription through ligand-dependent interactions with co-regulators and are involved in the development of secondary lymphoid tissues, autoimmune d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Jinshuo, Lv, Zhilei, Yang, Guanghai, Liao, Ting ting, Xu, Juanjuan, Wu, Feng, Huang, Qi, Guo, Mengfei, Hu, Guorong, Zhou, Mei, Duan, Limin, Liu, Shuqing, Jin, Yang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990620/ https://www.ncbi.nlm.nih.gov/pubmed/29904382 http://dx.doi.org/10.3389/fimmu.2018.01187

Ejemplares similares

Nanoparticles Targeting Macrophages as Potential Clinical Therapeutic Agents Against Cancer and Inflammation
por: Hu, Guorong, et al.
Publicado: (2019)

Comprehensive genomic and prognostic analysis of the IL-17 family genes in lung cancer
por: Liao, Tingting, et al.
Publicado: (2019)

The ACE2/Angiotensin-(1–7)/Mas Receptor Axis: Pleiotropic Roles in Cancer
por: Xu, Juanjuan, et al.
Publicado: (2017)

Role for Retinoic Acid-Related Orphan Receptor Alpha (RORα) Expressing Macrophages in Diet-Induced Obesity
por: Hams, Emily, et al.
Publicado: (2020)

The role of retinoic acid receptor-related orphan receptors in skeletal diseases
por: Zhang, Yifan, et al.
Publicado: (2023)

Functions for Retinoic Acid-Related Orphan Receptor Alpha (RORα) in the Activation of Macrophages During Lipopolysaccharide-Induced Septic Shock
por: Hams, Emily, et al.
Publicado: (2021)

Targeting Inflammatory T Helper Cells via Retinoic Acid-Related Orphan Receptor Gamma t Is Ineffective to Prevent Allo-Response-Driven Colitis
por: Buchele, Vera, et al.
Publicado: (2018)

Unraveling the physiological roles of retinoic acid receptor-related orphan receptor α
por: Lee, Ji Min, et al.
Publicado: (2021)

The Role of Interleukin-17 in Lung Cancer
por: Wu, Feng, et al.
Publicado: (2016)

Value of (18)F–FDG PET/CT for predicting EGFR mutations and positive ALK expression in patients with non-small cell lung cancer: a retrospective analysis of 849 Chinese patients
por: Lv, Zhilei, et al.
Publicado: (2017)

The Correlation Between Clinical Features and Viral RNA Shedding in Outpatients With COVID-19
por: Liao, Tingting, et al.
Publicado: (2020)

Immunoregulatory Roles of Extracellular Vesicles and Associated Therapeutic Applications in Lung Cancer
por: Yin, Zhengrong, et al.
Publicado: (2020)

Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid–Activated Receptor
por: Kruse, Schoen W, et al.
Publicado: (2008)

The role of the orphan nuclear receptor COUP-TFII in tumorigenesis
por: Xu, Mafei, et al.
Publicado: (2015)

IL-17 Promotes Angiogenic Factors IL-6, IL-8, and Vegf Production via Stat1 in Lung Adenocarcinoma
por: Huang, Qi, et al.
Publicado: (2016)

Antagonizing Retinoic Acid-Related-Orphan Receptor Gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses
por: Ecoeur, Florence, et al.
Publicado: (2019)

A fourth subtype of retinoic acid receptor-related orphan receptors is activated by oxidized all-trans retinoic acid in medaka (Oryzias latipes)
por: Sakai, Kotowa, et al.
Publicado: (2017)

Regulation of Expression of Citrate Synthase by the Retinoic Acid Receptor-Related Orphan Receptor α (RORα)
por: Crumbley, Christine, et al.
Publicado: (2012)

Synthesis of A-9758, an Inverse Agonist of Retinoic Acid-Related Orphan Receptor γt
por: Marvin, Christopher C., et al.
Publicado: (2022)

Virtual Screening Strategy to Identify Retinoic Acid-Related Orphan Receptor γt Modulators
por: Jokinen, Elmeri M., et al.
Publicado: (2023)

Transcription Factor Retinoid-Related Orphan Receptor γt: A Promising Target for the Treatment of Psoriasis
por: Tang, Lipeng, et al.
Publicado: (2018)

Ligand-Based Design of Allosteric Retinoic Acid Receptor-Related Orphan Receptor γt (RORγt) Inverse Agonists
por: Meijer, Femke A., et al.
Publicado: (2019)

Retinoic Acid Receptor-Related Receptor Alpha Ameliorates Autoimmune Arthritis via Inhibiting of Th17 Cells and Osteoclastogenesis
por: Park, Jin-Sil, et al.
Publicado: (2019)

Orphan receptors.
Publicado: (1993)

Retinoic Acid-Related Orphan Receptors (RORs): Regulatory Functions in Immunity, Development, Circadian Rhythm, and Metabolism
por: Cook, Donald N., et al.
Publicado: (2015)

Structure–Activity Relationship Studies of Trisubstituted Isoxazoles as Selective Allosteric Ligands for the Retinoic-Acid-Receptor-Related Orphan Receptor γt
por: Meijer, Femke A., et al.
Publicado: (2021)

KIR2DL5: An Orphan Inhibitory Receptor Displaying Complex Patterns of Polymorphism and Expression
por: Cisneros, Elisa, et al.
Publicado: (2012)

Corrigendum: IL-17 Promotes Angiogenic Factors IL-6, IL-8, and Vegf Production via Stat1 in Lung Adenocarcinoma
por: Huang, Qi, et al.
Publicado: (2017)

Retinoic acid-inducible gene-I like receptor pathway in cancer: modification and treatment
por: Du, Guangyuan, et al.
Publicado: (2023)

Immunoglobulin Expression in Cancer Cells and Its Critical Roles in Tumorigenesis
por: Cui, Ming, et al.
Publicado: (2021)

Phosphoenolpyruvate Carboxykinase, a Key Enzyme That Controls Blood Glucose, Is a Target of Retinoic Acid Receptor-Related Orphan Receptor α
por: Matsuoka, Hiroshi, et al.
Publicado: (2015)

Genetic Variants of Retinoic Acid Receptor-Related Orphan Receptor Alpha Determine Susceptibility to Type 2 Diabetes Mellitus in Han Chinese
por: Zhang, Yuwei, et al.
Publicado: (2016)

Retinoic acid receptor-related orphan receptor α reduces lipid droplets by upregulating neutral cholesterol ester hydrolase 1 in macrophages
por: Matsuoka, Hiroshi, et al.
Publicado: (2020)

Clinical Characteristics and Outcomes of Severe or Critical COVID-19 Patients Presenting No Respiratory Symptoms or Fever at Onset
por: Xu, Juanjuan, et al.
Publicado: (2021)

Association among Vitamin D, Retinoic Acid-Related Orphan Receptors, and Vitamin D Hydroxyderivatives in Ovarian Cancer
por: Brożyna, Anna A., et al.
Publicado: (2020)

High retinoic acid receptor-related orphan receptor A gene expression in peripheral blood leukocytes may be related to acute myocardial infarction
por: Meng, Heyu, et al.
Publicado: (2021)

Retinoic acid-related orphan receptor γ directly regulates neuronal PAS domain protein 2 transcription in vivo
por: Takeda, Yukimasa, et al.
Publicado: (2011)

Control of Gene Expression by the Retinoic Acid-Related Orphan Receptor Alpha in HepG2 Human Hepatoma Cells
por: Chauvet, Caroline, et al.
Publicado: (2011)

Retinoic acid-related orphan receptors α and γ: key regulators of lipid/glucose metabolism, inflammation, and insulin sensitivity
por: Jetten, Anton M., et al.
Publicado: (2013)

Discovery of Retinoic Acid-Related Orphan Receptor γt Inverse Agonists via Docking and Negative Image-Based Screening
por: Rauhamäki, Sanna, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_6ma147o3niijht883s3m2vd1vb