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Rhes Counteracts Dopamine Neuron Degeneration and Neuroinflammation Depending on Gender and Age

We have recently shown that male Rhes knockout (KO) mice develop a mild form of spontaneous Parkinson’s disease (PD)-like phenotype, characterized by motor impairment and a decrease in nigrostriatal dopamine (DA) neurons. Experimental evidence has implicated neuroinflammation in PD progression, and...

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Detalles Bibliográficos
Autores principales:	Costa, Giulia, Pinna, Annalisa, Porceddu, Pier Francesca, Casu, Maria Antonietta, Di Maio, Anna, Napolitano, Francesco, Usiello, Alessandro, Morelli, Micaela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990628/ https://www.ncbi.nlm.nih.gov/pubmed/29904346 http://dx.doi.org/10.3389/fnagi.2018.00163

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