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Targeting BCL-2 regulated apoptosis in cancer

The ability of a cell to undergo mitochondrial apoptosis is governed by pro- and anti-apoptotic members of the BCL-2 protein family. The equilibrium of pro- versus anti-apoptotic BCL-2 proteins ensures appropriate regulation of programmed cell death during development and maintains organismal health...

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Detalles Bibliográficos
Autores principales: Campbell, Kirsteen J., Tait, Stephen W. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990650/
https://www.ncbi.nlm.nih.gov/pubmed/29769323
http://dx.doi.org/10.1098/rsob.180002

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