Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus

Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) su...

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Autores principales: Li, Shuihong, Mou, Qianqian, Xu, Xinya, Qi, Shuhua, Leung, Polly H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society Publishing 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990757/
https://www.ncbi.nlm.nih.gov/pubmed/29892433
http://dx.doi.org/10.1098/rsos.172466
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author Li, Shuihong
Mou, Qianqian
Xu, Xinya
Qi, Shuhua
Leung, Polly H. M.
author_facet Li, Shuihong
Mou, Qianqian
Xu, Xinya
Qi, Shuhua
Leung, Polly H. M.
author_sort Li, Shuihong
collection PubMed
description Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections.
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spelling pubmed-59907572018-06-11 Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus Li, Shuihong Mou, Qianqian Xu, Xinya Qi, Shuhua Leung, Polly H. M. R Soc Open Sci Chemistry Penicillenol A2 (isolated from deep-sea fungus Penicillium biourgeianum DFFSCS023) has good antibacterial activity against methicillin-sensitive Staphylococcus aureus and in combination with beta-lactam antibiotics it could significantly decrease methicillin-resistant Staphylococcus aureus (MRSA) survival, which provides a novel treatment consideration for MRSA-caused infections. The Royal Society Publishing 2018-05-30 /pmc/articles/PMC5990757/ /pubmed/29892433 http://dx.doi.org/10.1098/rsos.172466 Text en © 2018 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.
spellingShingle Chemistry
Li, Shuihong
Mou, Qianqian
Xu, Xinya
Qi, Shuhua
Leung, Polly H. M.
Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus
title Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus
title_full Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus
title_fullStr Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus
title_full_unstemmed Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus
title_short Synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant Staphylococcus aureus
title_sort synergistic antibacterial activity between penicillenols and antibiotics against methicillin-resistant staphylococcus aureus
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990757/
https://www.ncbi.nlm.nih.gov/pubmed/29892433
http://dx.doi.org/10.1098/rsos.172466
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AT xuxinya synergisticantibacterialactivitybetweenpenicillenolsandantibioticsagainstmethicillinresistantstaphylococcusaureus
AT qishuhua synergisticantibacterialactivitybetweenpenicillenolsandantibioticsagainstmethicillinresistantstaphylococcusaureus
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