Cargando…
Individual-based modelling and control of bovine brucellosis
We present a theoretical approach to control bovine brucellosis. We have used individual-based modelling, which is a network-type alternative to compartmental models. Our model thus considers heterogeneous populations, and spatial aspects such as migration among herds and control actions described a...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society Publishing
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990817/ https://www.ncbi.nlm.nih.gov/pubmed/29892455 http://dx.doi.org/10.1098/rsos.180200 |
_version_ | 1783329657424183296 |
---|---|
author | Nepomuceno, Erivelton G. Barbosa, Alípio M. Silva, Marcos X. Perc, Matjaž |
author_facet | Nepomuceno, Erivelton G. Barbosa, Alípio M. Silva, Marcos X. Perc, Matjaž |
author_sort | Nepomuceno, Erivelton G. |
collection | PubMed |
description | We present a theoretical approach to control bovine brucellosis. We have used individual-based modelling, which is a network-type alternative to compartmental models. Our model thus considers heterogeneous populations, and spatial aspects such as migration among herds and control actions described as pulse interventions are also easily implemented. We show that individual-based modelling reproduces the mean field behaviour of an equivalent compartmental model. Details of this process, as well as flowcharts, are provided to facilitate the reproduction of the presented results. We further investigate three numerical examples using real parameters of herds in the São Paulo state of Brazil, in scenarios which explore eradication, continuous and pulsed vaccination and meta-population effects. The obtained results are in good agreement with the expected behaviour of this disease, which ultimately showcases the effectiveness of our theory. |
format | Online Article Text |
id | pubmed-5990817 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | The Royal Society Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-59908172018-06-11 Individual-based modelling and control of bovine brucellosis Nepomuceno, Erivelton G. Barbosa, Alípio M. Silva, Marcos X. Perc, Matjaž R Soc Open Sci Engineering We present a theoretical approach to control bovine brucellosis. We have used individual-based modelling, which is a network-type alternative to compartmental models. Our model thus considers heterogeneous populations, and spatial aspects such as migration among herds and control actions described as pulse interventions are also easily implemented. We show that individual-based modelling reproduces the mean field behaviour of an equivalent compartmental model. Details of this process, as well as flowcharts, are provided to facilitate the reproduction of the presented results. We further investigate three numerical examples using real parameters of herds in the São Paulo state of Brazil, in scenarios which explore eradication, continuous and pulsed vaccination and meta-population effects. The obtained results are in good agreement with the expected behaviour of this disease, which ultimately showcases the effectiveness of our theory. The Royal Society Publishing 2018-05-02 /pmc/articles/PMC5990817/ /pubmed/29892455 http://dx.doi.org/10.1098/rsos.180200 Text en © 2018 The Authors. http://creativecommons.org/licenses/by/4.0/ Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited. |
spellingShingle | Engineering Nepomuceno, Erivelton G. Barbosa, Alípio M. Silva, Marcos X. Perc, Matjaž Individual-based modelling and control of bovine brucellosis |
title | Individual-based modelling and control of bovine brucellosis |
title_full | Individual-based modelling and control of bovine brucellosis |
title_fullStr | Individual-based modelling and control of bovine brucellosis |
title_full_unstemmed | Individual-based modelling and control of bovine brucellosis |
title_short | Individual-based modelling and control of bovine brucellosis |
title_sort | individual-based modelling and control of bovine brucellosis |
topic | Engineering |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5990817/ https://www.ncbi.nlm.nih.gov/pubmed/29892455 http://dx.doi.org/10.1098/rsos.180200 |
work_keys_str_mv | AT nepomucenoeriveltong individualbasedmodellingandcontrolofbovinebrucellosis AT barbosaalipiom individualbasedmodellingandcontrolofbovinebrucellosis AT silvamarcosx individualbasedmodellingandcontrolofbovinebrucellosis AT percmatjaz individualbasedmodellingandcontrolofbovinebrucellosis |