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α-Klotho's effects on mineral homeostasis are fibroblast growth factor-23 dependent
PURPOSE OF REVIEW: α-Klotho (Klotho) occurs in three isoforms, a membrane-bound form acting as a coreceptor for fibroblast growth factor-23 (FGF23) signalling, a shed soluble form consisting of Klotho's large ectodomain thought to act as an enzyme or a hormone, and a secreted truncated form gen...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Lippincott Williams & Wilkins
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991181/ https://www.ncbi.nlm.nih.gov/pubmed/29851418 http://dx.doi.org/10.1097/MNH.0000000000000415 |