Rare variants in RNF213, a susceptibility gene for moyamoya disease, are found in patients with pulmonary hypertension and aggravate hypoxia-induced pulmonary hypertension in mice

Ring finger 213 (RNF213) is a susceptibility gene for moyamoya disease (MMD), a progressive cerebrovascular disease. Recent studies suggest that RNF213 plays an important role not only in MMD, but also in extracranial vascular diseases, such as pulmonary hypertension (PH). In this study, we undertoo...

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Detalles Bibliográficos
Autores principales: Kobayashi, Hatasu, Kabata, Risako, Kinoshita, Hideyuki, Morimoto, Takaaki, Ono, Koh, Takeda, Midori, Choi, Jungmi, Okuda, Hiroko, Liu, Wanyang, Harada, Kouji H., Kimura, Takeshi, Youssefian, Shohab, Koizumi, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991195/
https://www.ncbi.nlm.nih.gov/pubmed/29718794
http://dx.doi.org/10.1177/2045894018778155

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