Chronic social stress induces peripheral and central immune activation, blunted mesolimbic dopamine function, and reduced reward-directed behaviour in mice

Psychosocial stress is a major risk factor for depression, stress leads to peripheral and central immune activation, immune activation is associated with blunted dopamine (DA) neural function, DA function underlies reward interest, and reduced reward interest is a core symptom of depression. These s...

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Detalles Bibliográficos
Autores principales: Bergamini, Giorgio, Mechtersheimer, Jonas, Azzinnari, Damiano, Sigrist, Hannes, Buerge, Michaela, Dallmann, Robert, Freije, Robert, Kouraki, Afroditi, Opacka-Juffry, Jolanta, Seifritz, Erich, Ferger, Boris, Suter, Tobias, Pryce, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991330/
https://www.ncbi.nlm.nih.gov/pubmed/29888303
http://dx.doi.org/10.1016/j.ynstr.2018.01.004

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