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A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals

BACKGROUND: Ebola virus (EBOV) caused more than 11,000 deaths during the 2013–2016 epidemic in West Africa without approved vaccines or immunotherapeutics. Despite its high lethality in some individuals, EBOV infection can produce little to no symptoms in others. A better understanding of the immune...

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Detalles Bibliográficos
Autores principales: Herrera, Bobby Brooke, Hamel, Donald J., Oshun, Philip, Akinsola, Rolake, Akanmu, Alani S., Chang, Charlotte A., Eromon, Philomena, Folarin, Onikepe, Adeyemi, Kayode T., Happi, Christian T., Lu, Yichen, Ogunsola, Folasade, Kanki, Phyllis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991402/
https://www.ncbi.nlm.nih.gov/pubmed/29795572
http://dx.doi.org/10.1371/journal.pntd.0006530