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A computational model for the evaluation of complement system regulation under homeostasis, disease, and drug intervention
The complement system is an intricate defense network that rapidly removes invading pathogens. Although many complement regulators are present to protect host cells under homeostasis, the impairment of Factor H (FH) regulatory mechanism has been associated with several autoimmune and inflammatory di...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991421/ https://www.ncbi.nlm.nih.gov/pubmed/29874282 http://dx.doi.org/10.1371/journal.pone.0198644 |