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Was Muller’s 1946 Nobel Prize research for radiation-induced gene mutations peer-reviewed?
This historical analysis indicates that it is highly unlikely that the Nobel Prize winning research of Hermann J. Muller was peer-reviewed. The published paper of Muller lacked a research methods section, cited no references, and failed to acknowledge and discuss the work of Gager and Blakeslee (PNA...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991452/ https://www.ncbi.nlm.nih.gov/pubmed/29875023 http://dx.doi.org/10.1186/s13010-018-0060-5 |
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author | Calabrese, Edward J. |
author_facet | Calabrese, Edward J. |
author_sort | Calabrese, Edward J. |
collection | PubMed |
description | This historical analysis indicates that it is highly unlikely that the Nobel Prize winning research of Hermann J. Muller was peer-reviewed. The published paper of Muller lacked a research methods section, cited no references, and failed to acknowledge and discuss the work of Gager and Blakeslee (PNAS 13:75-79, 1927) that claimed to have induced gene mutation via ionizing radiation six months prior to Muller’s non-data Science paper (Muller, Science 66(1699):84-87, 1927a). Despite being well acclimated into the scientific world of peer-review, Muller choose to avoid the peer-review process on his most significant publication. It appears that Muller’s actions were strongly influenced by his desire to claim primacy for the discovery of gene mutation. The actions of Muller have important ethical lessons and implications today, when self-interest trumps one’s obligations to society and the scientific culture that supports the quest for new knowledge and discovery. |
format | Online Article Text |
id | pubmed-5991452 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-59914522018-06-21 Was Muller’s 1946 Nobel Prize research for radiation-induced gene mutations peer-reviewed? Calabrese, Edward J. Philos Ethics Humanit Med Review This historical analysis indicates that it is highly unlikely that the Nobel Prize winning research of Hermann J. Muller was peer-reviewed. The published paper of Muller lacked a research methods section, cited no references, and failed to acknowledge and discuss the work of Gager and Blakeslee (PNAS 13:75-79, 1927) that claimed to have induced gene mutation via ionizing radiation six months prior to Muller’s non-data Science paper (Muller, Science 66(1699):84-87, 1927a). Despite being well acclimated into the scientific world of peer-review, Muller choose to avoid the peer-review process on his most significant publication. It appears that Muller’s actions were strongly influenced by his desire to claim primacy for the discovery of gene mutation. The actions of Muller have important ethical lessons and implications today, when self-interest trumps one’s obligations to society and the scientific culture that supports the quest for new knowledge and discovery. BioMed Central 2018-06-06 /pmc/articles/PMC5991452/ /pubmed/29875023 http://dx.doi.org/10.1186/s13010-018-0060-5 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Review Calabrese, Edward J. Was Muller’s 1946 Nobel Prize research for radiation-induced gene mutations peer-reviewed? |
title | Was Muller’s 1946 Nobel Prize research for radiation-induced gene mutations peer-reviewed? |
title_full | Was Muller’s 1946 Nobel Prize research for radiation-induced gene mutations peer-reviewed? |
title_fullStr | Was Muller’s 1946 Nobel Prize research for radiation-induced gene mutations peer-reviewed? |
title_full_unstemmed | Was Muller’s 1946 Nobel Prize research for radiation-induced gene mutations peer-reviewed? |
title_short | Was Muller’s 1946 Nobel Prize research for radiation-induced gene mutations peer-reviewed? |
title_sort | was muller’s 1946 nobel prize research for radiation-induced gene mutations peer-reviewed? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991452/ https://www.ncbi.nlm.nih.gov/pubmed/29875023 http://dx.doi.org/10.1186/s13010-018-0060-5 |
work_keys_str_mv | AT calabreseedwardj wasmullers1946nobelprizeresearchforradiationinducedgenemutationspeerreviewed |