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The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice
BACKGROUND: The role of PPARα in gene regulation in mouse liver is well characterized. However, less is known about the role of PPARα in human liver. The aim of the present study was to better characterize the impact of PPARα activation on gene regulation in human liver. To that end, chimeric mice c...
Autores principales: | de la Rosa Rodriguez, Montserrat A., Sugahara, Go, Hooiveld, Guido J. E. J., Ishida, Yuji, Tateno, Chise, Kersten, Sander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991453/ https://www.ncbi.nlm.nih.gov/pubmed/29879903 http://dx.doi.org/10.1186/s12864-018-4834-3 |
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