A novel k-mer set memory (KSM) motif representation improves regulatory variant prediction

The representation and discovery of transcription factor (TF) sequence binding specificities is critical for understanding gene regulatory networks and interpreting the impact of disease-associated noncoding genetic variants. We present a novel TF binding motif representation, the k-mer set memory (...

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Detalles Bibliográficos
Autores principales: Guo, Yuchun, Tian, Kevin, Zeng, Haoyang, Guo, Xiaoyun, Gifford, David Kenneth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991515/
https://www.ncbi.nlm.nih.gov/pubmed/29654070
http://dx.doi.org/10.1101/gr.226852.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991515/
https://www.ncbi.nlm.nih.gov/pubmed/29654070
http://dx.doi.org/10.1101/gr.226852.117

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