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A novel k-mer set memory (KSM) motif representation improves regulatory variant prediction
The representation and discovery of transcription factor (TF) sequence binding specificities is critical for understanding gene regulatory networks and interpreting the impact of disease-associated noncoding genetic variants. We present a novel TF binding motif representation, the k-mer set memory (...
Autores principales: | Guo, Yuchun, Tian, Kevin, Zeng, Haoyang, Guo, Xiaoyun, Gifford, David Kenneth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991515/ https://www.ncbi.nlm.nih.gov/pubmed/29654070 http://dx.doi.org/10.1101/gr.226852.117 |
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