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The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes

Retrotransposons encompass half of the human genome and contribute to the formation of heterochromatin, which provides nuclear structure and regulates gene expression. Here, we asked if the human silencing hub (HUSH) complex is necessary to silence retrotransposons and whether it collaborates with T...

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Detalles Bibliográficos
Autores principales:	Robbez-Masson, Luisa, Tie, Christopher H.C., Conde, Lucia, Tunbak, Hale, Husovsky, Connor, Tchasovnikarova, Iva A., Timms, Richard T., Herrero, Javier, Lehner, Paul J., Rowe, Helen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991525/ https://www.ncbi.nlm.nih.gov/pubmed/29728366 http://dx.doi.org/10.1101/gr.228171.117

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