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Enhancement of red blood cell transfusion compatibility using CRISPR‐mediated erythroblast gene editing

Regular blood transfusion is the cornerstone of care for patients with red blood cell (RBC) disorders such as thalassaemia or sickle‐cell disease. With repeated transfusion, alloimmunisation often occurs due to incompatibility at the level of minor blood group antigens. We use CRISPR‐mediated genome...

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Detalles Bibliográficos
Autores principales:	Hawksworth, Joseph, Satchwell, Timothy J, Meinders, Marjolein, Daniels, Deborah E, Regan, Fiona, Thornton, Nicole M, Wilson, Marieangela C, Dobbe, Johannes GG, Streekstra, Geert J, Trakarnsanga, Kongtana, Heesom, Kate J, Anstee, David J, Frayne, Jan, Toye, Ashley M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991592/ https://www.ncbi.nlm.nih.gov/pubmed/29700043 http://dx.doi.org/10.15252/emmm.201708454

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