Changes of MODY signal pathway genes in the endoplasmic reticulum stress in INS-1-3 cells

OBJECTIVE: Metabolic disturbances induce endoplasmic reticulum stress (ERS) in pancreatic beta cells. This study aims to investigate whether a common pathway exists in the ERS induced by various chemicals, including high levels of glucose and palmitate in INS-1-3 cells. METHOD: ERS in INS-1-3 cells...

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Detalles Bibliográficos
Autores principales: Dong, Yanan, Li, Shirui, Zhao, Wenhui, Wang, Yanlei, Ge, Tingting, Xiao, Jianzhong, Li, Yukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991669/
https://www.ncbi.nlm.nih.gov/pubmed/29879176
http://dx.doi.org/10.1371/journal.pone.0198614

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