A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report

Familial hypercholesterolemia (FH) is a genetic disease associated with persistently elevated levels of low-density lipoprotein cholesterol (LDL-C), which ultimately leads to greatly increased rates of atherosclerosis and cardiovascular disease. Atherosclerosis progression can be clinically approxim...

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Detalles Bibliográficos
Autores principales: Johnson, Kipp W, Dudley, Joel T, Bobe, Jason R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Cardiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991918/
https://www.ncbi.nlm.nih.gov/pubmed/29888156
http://dx.doi.org/10.7759/cureus.2452
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author Johnson, Kipp W
Dudley, Joel T
Bobe, Jason R
author_facet Johnson, Kipp W
Dudley, Joel T
Bobe, Jason R
author_sort Johnson, Kipp W
collection PubMed
description Familial hypercholesterolemia (FH) is a genetic disease associated with persistently elevated levels of low-density lipoprotein cholesterol (LDL-C), which ultimately leads to greatly increased rates of atherosclerosis and cardiovascular disease. Atherosclerosis progression can be clinically approximated through measurement of coronary artery calcification (CAC). CAC can be measured via electron beam computed tomography (EBCT), multi-slice computed tomography (MSCT), or contrast-enhanced CT coronary angiography (CTCA). Here, we present the case of a 72-year-old man with known FH and established hypercholesterolemia who has consistently tested negative for any significant CAC.
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spelling pubmed-59919182018-06-08 A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report Johnson, Kipp W Dudley, Joel T Bobe, Jason R Cureus Cardiology Familial hypercholesterolemia (FH) is a genetic disease associated with persistently elevated levels of low-density lipoprotein cholesterol (LDL-C), which ultimately leads to greatly increased rates of atherosclerosis and cardiovascular disease. Atherosclerosis progression can be clinically approximated through measurement of coronary artery calcification (CAC). CAC can be measured via electron beam computed tomography (EBCT), multi-slice computed tomography (MSCT), or contrast-enhanced CT coronary angiography (CTCA). Here, we present the case of a 72-year-old man with known FH and established hypercholesterolemia who has consistently tested negative for any significant CAC. Cureus 2018-04-09 /pmc/articles/PMC5991918/ /pubmed/29888156 http://dx.doi.org/10.7759/cureus.2452 Text en Copyright © 2018, Johnson et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Johnson, Kipp W
Dudley, Joel T
Bobe, Jason R
A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report
title A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report
title_full A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report
title_fullStr A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report
title_full_unstemmed A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report
title_short A 72-Year-Old Patient with Longstanding, Untreated Familial Hypercholesterolemia but no Coronary Artery Calcification: A Case Report
title_sort 72-year-old patient with longstanding, untreated familial hypercholesterolemia but no coronary artery calcification: a case report
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991918/
https://www.ncbi.nlm.nih.gov/pubmed/29888156
http://dx.doi.org/10.7759/cureus.2452
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