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Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer

Introduction Breast cancer has a high prevalence in the community and places very high demands on resources. Digital mammography provides a good quality image with reduced radiation dose and can detect breast carcinoma in its earlier stages, resulting in good prognosis and improved patient survival....

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Autores principales: Zeeshan, Muhammad, Salam, Basit, Khalid, Qazi Saad B, Alam, Shahbaz, Sayani, Raza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991925/
https://www.ncbi.nlm.nih.gov/pubmed/29888152
http://dx.doi.org/10.7759/cureus.2448
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author Zeeshan, Muhammad
Salam, Basit
Khalid, Qazi Saad B
Alam, Shahbaz
Sayani, Raza
author_facet Zeeshan, Muhammad
Salam, Basit
Khalid, Qazi Saad B
Alam, Shahbaz
Sayani, Raza
author_sort Zeeshan, Muhammad
collection PubMed
description Introduction Breast cancer has a high prevalence in the community and places very high demands on resources. Digital mammography provides a good quality image with reduced radiation dose and can detect breast carcinoma in its earlier stages, resulting in good prognosis and improved patient survival. Objective To calculate the diagnostic accuracy of digital mammography in the detection of breast cancer, using histopathology as a gold standard in women aged over 30 years, who are undergoing mammography for screening and diagnostic purposes. Materials and methods This was a cross-sectional analytical study, conducted in the department of radiology, for a total duration of 10 months. A total of 122 patients of age above 30 years, referred for digital mammography for the evaluation of different symptoms related to breast diseases, followed by biopsy/surgery and histopathology, were included in the study. Result Our data confirmed that digital mammography is a highly accurate tool for breast cancer detection having a sensitivity of 97%, a specificity of 64.5%, a positive predictive value of 89%, and a negative predictive value of 90.9%, with a diagnostic accuracy of 89.3%. Conclusion Considering our results, we recommend that digital mammography should replace screen-film mammography as a basic tool to detect breast cancer for both screening and diagnostic purposes.
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spelling pubmed-59919252018-06-08 Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer Zeeshan, Muhammad Salam, Basit Khalid, Qazi Saad B Alam, Shahbaz Sayani, Raza Cureus Pathology Introduction Breast cancer has a high prevalence in the community and places very high demands on resources. Digital mammography provides a good quality image with reduced radiation dose and can detect breast carcinoma in its earlier stages, resulting in good prognosis and improved patient survival. Objective To calculate the diagnostic accuracy of digital mammography in the detection of breast cancer, using histopathology as a gold standard in women aged over 30 years, who are undergoing mammography for screening and diagnostic purposes. Materials and methods This was a cross-sectional analytical study, conducted in the department of radiology, for a total duration of 10 months. A total of 122 patients of age above 30 years, referred for digital mammography for the evaluation of different symptoms related to breast diseases, followed by biopsy/surgery and histopathology, were included in the study. Result Our data confirmed that digital mammography is a highly accurate tool for breast cancer detection having a sensitivity of 97%, a specificity of 64.5%, a positive predictive value of 89%, and a negative predictive value of 90.9%, with a diagnostic accuracy of 89.3%. Conclusion Considering our results, we recommend that digital mammography should replace screen-film mammography as a basic tool to detect breast cancer for both screening and diagnostic purposes. Cureus 2018-04-08 /pmc/articles/PMC5991925/ /pubmed/29888152 http://dx.doi.org/10.7759/cureus.2448 Text en Copyright © 2018, Zeeshan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Zeeshan, Muhammad
Salam, Basit
Khalid, Qazi Saad B
Alam, Shahbaz
Sayani, Raza
Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer
title Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer
title_full Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer
title_fullStr Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer
title_full_unstemmed Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer
title_short Diagnostic Accuracy of Digital Mammography in the Detection of Breast Cancer
title_sort diagnostic accuracy of digital mammography in the detection of breast cancer
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5991925/
https://www.ncbi.nlm.nih.gov/pubmed/29888152
http://dx.doi.org/10.7759/cureus.2448
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