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Aberrant mannosylation profile and FTX/miR-342/ALG3-axis contribute to development of drug resistance in acute myeloid leukemia

Drug-resistance is a major problem in acute myeloid leukemia (AML) chemotherapy. Aberrant changes in specific N-glycans have been observed in leukemia multidrug resistance (MDR). MicroRNAs (miRNAs) and long non coding RNAs (lncRNAs) act as key players in the development of AML resistance to chemothe...

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Detalles Bibliográficos
Autores principales:	Liu, Bing, Ma, Xiaolu, Liu, Qianqian, Xiao, Yang, Pan, Shimeng, Jia, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992136/ https://www.ncbi.nlm.nih.gov/pubmed/29880818 http://dx.doi.org/10.1038/s41419-018-0706-7

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