Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints

Cell growth and survival depend on a delicate balance between energy production and synthesis of metabolites. Here, we provide evidence that an alternative mitochondrial complex II (CII) assembly, designated as CII(low), serves as a checkpoint for metabolite biosynthesis under bioenergetic stress, w...

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Detalles Bibliográficos
Autores principales: Bezawork-Geleta, Ayenachew, Wen, He, Dong, LanFeng, Yan, Bing, Vider, Jelena, Boukalova, Stepana, Krobova, Linda, Vanova, Katerina, Zobalova, Renata, Sobol, Margarita, Hozak, Pavel, Novais, Silvia Magalhaes, Caisova, Veronika, Abaffy, Pavel, Naraine, Ravindra, Pang, Ying, Zaw, Thiri, Zhang, Ping, Sindelka, Radek, Kubista, Mikael, Zuryn, Steven, Molloy, Mark P., Berridge, Michael V., Pacak, Karel, Rohlena, Jakub, Park, Sunghyouk, Neuzil, Jiri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992162/
https://www.ncbi.nlm.nih.gov/pubmed/29880867
http://dx.doi.org/10.1038/s41467-018-04603-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992162/
https://www.ncbi.nlm.nih.gov/pubmed/29880867
http://dx.doi.org/10.1038/s41467-018-04603-z

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