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Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints
Cell growth and survival depend on a delicate balance between energy production and synthesis of metabolites. Here, we provide evidence that an alternative mitochondrial complex II (CII) assembly, designated as CII(low), serves as a checkpoint for metabolite biosynthesis under bioenergetic stress, w...
Autores principales: | Bezawork-Geleta, Ayenachew, Wen, He, Dong, LanFeng, Yan, Bing, Vider, Jelena, Boukalova, Stepana, Krobova, Linda, Vanova, Katerina, Zobalova, Renata, Sobol, Margarita, Hozak, Pavel, Novais, Silvia Magalhaes, Caisova, Veronika, Abaffy, Pavel, Naraine, Ravindra, Pang, Ying, Zaw, Thiri, Zhang, Ping, Sindelka, Radek, Kubista, Mikael, Zuryn, Steven, Molloy, Mark P., Berridge, Michael V., Pacak, Karel, Rohlena, Jakub, Park, Sunghyouk, Neuzil, Jiri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992162/ https://www.ncbi.nlm.nih.gov/pubmed/29880867 http://dx.doi.org/10.1038/s41467-018-04603-z |
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