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A Review of Notch Processing With New Insights Into Ligand-Independent Notch Signaling in T-Cells
The Notch receptor is an evolutionarily highly conserved transmembrane protein essential to a wide spectrum of cellular systems, and its deregulation has been linked to a vast number of developmental disorders and malignancies. Regulated Notch function is critical for the generation of T-cells, in w...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992298/ https://www.ncbi.nlm.nih.gov/pubmed/29910816 http://dx.doi.org/10.3389/fimmu.2018.01230 |