A mathematical framework for yield (vs. rate) optimization in constraint-based modeling and applications in metabolic engineering

Background: The optimization of metabolic rates (as linear objective functions) represents the methodical core of flux-balance analysis techniques which have become a standard tool for the study of genome-scale metabolic models. Besides (growth and synthesis) rates, metabolic yields are key paramete...

Descripción completa

Detalles Bibliográficos
Autores principales: Klamt, Steffen, Müller, Stefan, Regensburger, Georg, Zanghellini, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992331/
https://www.ncbi.nlm.nih.gov/pubmed/29427605
http://dx.doi.org/10.1016/j.ymben.2018.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992331/
https://www.ncbi.nlm.nih.gov/pubmed/29427605
http://dx.doi.org/10.1016/j.ymben.2018.02.001

Ejemplares similares